ICSI is an advanced form of IVF where a single healthy sperm is directly injected into a mature egg using microscopic techniques. This method is especially helpful for couples facing male infertility issues, such as low sperm count, poor sperm motility, or abnormal sperm shape. Once fertilization occurs, the embryo is transferred to the uterus, similar to standard IVF. ICSI significantly improves fertilization chances when natural sperm-egg binding is a challenge.